Recombinant Human NSF GST (N-Term) Protein

This product is produced by and distributed for Abnova, a company based in Taiwan.

N ethylmaleimide sensitive factor (NSF) is an ~83 kDa protein (predicted MW) which was initially isolated based on its ability to restore intercisternal Golgi transport to N ethylmaleimide treated membranes. NSF was subsequently discovered to be involved in a variety of membrane fusion events. NSF is an ATPase with two ATP binding domains that are essential for membrane fusion and homo oligomerization. In order to interact with target membranes, NSF requires another set of soluble proteins called Soluble NSF attachment proteins (SNAPs). NSF has been shown to play a prominent role in synaptic vesicle fusion. Together with synaptotagmin and a SNAP, NSF modulates the interaction of SNAP25, VAMP, and syntaxin, in an ATP dependent manner, to form a complex with a sedimentation coefficient of 20 S. This complex may represent an intermediate involved in synaptic vesicle docking and fusion.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IP.

Showing Publication 1 - 1 of 1.

Publication using H00004905-P01	Applications	Species
Gokhale A, Mullin AP, Zlatic SA et al. The N-Ethylmaleimide-Sensitive Factor and Dysbindin Interact To Modulate Synaptic Plasticity. J Neurosci 2015-05-13 [PMID: 25972187] (IP, Human)	IP	Human

Array H00004905-P01

• NSF Antibodies
• NSF ELISA Kits
• NSF Lysate
• NSF Proteins