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NPRB/NPR2 Antibody (2A6)

Images

 
Immunohistochemistry-Paraffin: NPRB/NPR2 Antibody (2A6) [H00004882-M01] - Analysis of monoclonal antibody to NPR2 on formalin-fixed paraffin-embedded human stomach. Antibody concentration 3 ug/ml.
Sandwich ELISA Capture: NPRB/NPR2 Antibody (2A6) [H00004882-M01] - Detection limit for recombinant GST tagged NPRB/NPR2 is 1 ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, ELISA
Clone
2A6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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NPRB/NPR2 Antibody (2A6) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
NPR2 (NP_003986.2, 131 a.a. ~ 230 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPL
Specificity
NPR2 (2A6)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NPR2
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Sandwich ELISA Capture
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NPRB/NPR2 Antibody (2A6)

  • AMD1;AMDM;ANPb;ANPRB;Atrial natriuretic peptide receptor 2;ECDM;GCB;GC-B;GUC2B;GUCY2B;NPRB;NPRBi;SNSK
  • AMDM
  • ANPb
  • ANPRB
  • ECDM
  • GC-B
  • GUC2B
  • NPR2
  • NPRB
  • NPRBi
  • SNSK

Background

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NPR2
Entrez
OMIM
Uniprot