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NMDAR2C Antibody

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Immunohistochemistry-Paraffin: NMDAR2C Antibody [NBP3-10352] - Immunohistochemical analysis of formalin-fixed paraffin-embedded human adult heart tissue.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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NMDAR2C Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NMDAR2C (NP_000826). Peptide sequence VNTTNPSSLLTQICGLLGAAHVHGIVFEDNVDTEAVAQILDFISSQTHVP
Specificity
Epsilon-3 subunit
Clonality
Polyclonal
Host
Rabbit
Gene
GRIN2C
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1.0 ug/ml
Theoretical MW
136 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for NMDAR2C Antibody

  • glutamate [NMDA] receptor subunit epsilon-3
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • GRIN2C
  • NMDA R, NR2C Subunit
  • NMDAR2C
  • NMDAR2CNR2C
  • N-methyl D-aspartate receptor subtype 2C
  • N-methyl-D-aspartate receptor subunit 2C
  • NR2C

Background

The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GRIN2C