NMDAR2B Antibody (S59) [Alexa Fluor® 647] Summary
Immunogen |
Fusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B |
Localization |
Cell Membrane , Cell Junction , Synapse , Postsynaptic Cell Membrane |
Specificity |
Detects approx 166kDa. No cross-reactivity against NR2A. |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
GRIN2B |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunoprecipitation
- Microarray
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein G purified |
Alternate Names for NMDAR2B Antibody (S59) [Alexa Fluor® 647]
Background
NMDA receptor 2B is an ion channels activated by glutamate. NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors like NMDAR2B also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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