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Neuregulin-1 beta 1/NRG1 beta 1 Antibody (147705) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA(Cap)
Clone
147705
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB3771-SP
Carrier Free
MAB3771-500
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Neuregulin-1 beta 1/NRG1 beta 1 Antibody (147705) [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human NRG1-beta 1/HRG1-beta 1
Ser2-Lys246
Accession # AAA58639
Specificity
Detects human NRG1-beta 1 in ELISAs. Recognizes an epitope found in the EGF-like domain of NRG1‑ beta 1 (amino acids 179‑246). It also detects recombinant human SMDF (Sensory and Motor neuron-Derived Factor), but it does not recognize the EGF-like domain of human NRG1-alpha (amino acids 177‑241). The epitope is present within amino acids 213‑230 of human NRG1-beta 1. This segment is present in all NRG1 beta isoforms, GGF‑2 (glial growth factor), and SMDF, but it is absent from NRG1-alpha , NDF43, and NRG1-gamma .
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NRG1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • ELISA Standard (Matched Pair)
Application Notes
ELISA Detection: Human NRG1-beta 1/HRG1-beta 1 Extracellular Domain Biotinylated Antibody (Catalog number BAF377)
Standard: Recombinant Human NRG1-beta 1/HRG1-beta 1 Extracellular Domain (Catalog number 377-HB)
Publications
Read Publications using
MAB3771 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neuregulin-1 beta 1/NRG1 beta 1 Antibody (147705) [Unconjugated]

  • ARIA
  • GGF
  • GGF2
  • HGL
  • HRG
  • HRG1
  • HRGA
  • MST131
  • MSTP131
  • NDF
  • neuregulin 1
  • Neuregulin1 beta 1
  • Neuregulin-1 beta 1
  • NRG1-IT2
  • SMDF

Background

Neuregulin-1, also known as Heregulin 1, functions as a ligand for the receptor tyrosine kinases, ErbB3 and ErbB4. It exists in several different mRNA splicing variants resulting in both transmembrane and secreted forms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Neuregulin-1 beta
1/NRG1 beta 1 Antibod ...
MAB3771
Neuregulin-1 beta 1/NRG1 beta 1 Antibody (147705) [Unconjugated]
Species: Hu
Applications: ELISA(Cap)

Publications for Neuregulin-1 beta 1/NRG1 beta 1 Antibody (MAB3771)(2)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 1 application: Western Blot.


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(2)
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(1)
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(1)
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(1)
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Bioinformatics

Gene Symbol NRG1
Uniprot