Nectin-2/CD112 Antibody (JG39-64) Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Recombinant protein within Human Nectin-2/CD112 aa 370-538 / 538. (SwissProt: Q92692 Human; SwissProt: P32507 Mouse; SwissProt: Q5FVC5 Rat) |
Localization |
Cell membrane. Membrane. |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
NECTIN2 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:50-1:100
- Immunocytochemistry/ Immunofluorescence 1:50
- Immunohistochemistry
- Immunohistochemistry-Paraffin 1:50-1:200
- Western Blot 1:500-1:2000
|
Theoretical MW |
58 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
TBS (pH7.4), 0.05% BSA, 40% Glycerol |
Preservative |
0.05% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Protein A purified |
Alternate Names for Nectin-2/CD112 Antibody (JG39-64)
Background
Nectin 2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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