Napsin A Antibody (TMU-Ad02)

NAPSA (Napsin A) is an aspartic proteinase that belongs to peptidase A1 family (NAPSA, cathepsins D and E, renin, pepsin, gastricsin, and bovine chymosin) and it is primarily expressed in lung and kidney, and at a very low levels in spleen as well as in peripheral blood leukocytes. NAPSA's expression is regulated by TTF-1 which also regulates the expression of surfactant protein B. Inside the lung, NAPSA is expressed in alveolar type II pneumocytes where it colocalize with prosurfactant B protein as well as surfactant B in the lamellar bodies, and has been suggested to be involved in N-terminal/C-terminal processing of prosurfactant B protein. NAPSA is also localized in intra-alveolar macrophages, probably as a result of phagocytosis. In renal tissues, NAPSA is expressed in the proximal tubules, where it is suggested to function as a lysosomal protease involved in protein catabolism.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publications 1 - 3 of 3.

Publications using NB110-68133	Applications	Species
Wang M, Chen PP, Cai G GATA3 Expression in Primary Lung Carcinomas: Correlation with Histopathologic Features and TTF-1, Napsin A, and p40 Expression Human pathology 2023-01-23 [PMID: 36702357] (IHC-P, Human) Details: Dilution used in IHC-P 1:4,000	IHC-P	Human
Hirano T, Gong Y, Yoshida K, Kato Y, Yashima K, Maeda M, Nakagawa A, Fujioka K, Ohira T, Ikeda N, Ebihara Y, Auer G, Kato H. Usefulness of TA02 (napsin A) to distinguish primary lung adenocarcinoma from metastatic lung adenocarcinoma. Lung Cancer;41(2):155-62. 2003-08-01 [PMID: 12871778] (IHC-P, Human)	IHC-P	Human
Hirano T, Auer G, Maeda M, Hagiwara Y, Okada S, Ohira T, Okuzawa K, Fujioka K, Franzen B, Hibi N, Seito T, Ebihara Y, Kato H. Human tissue distribution of TA02, which is homologous with a new type of aspartic proteinase, napsin A. Jpn J Cancer Res;91(10):1015-21. 2000-10-01 [PMID: 11050472]

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	IHC-P	Human	11/16/2009	View Summary Application Immunohistochemistry-Paraffin Sample Tested Human tissue Species Human Lot 60816

Array NB110-68133

• Napsin A Antibodies
• Napsin A Lysate
• Napsin A Proteins
• Napsin A Proteins and Enzyme