Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Simple Western, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Napsin is a pepsin-like aspartic proteinase, in the A1 clan of the AA clade of proteinases. Other AA family proteinases include Pepsin, cathepsin-D, cathepsin-E and rennin. Of these proteinases, napsin is most closely related to cathepsin-D, sharing 46% identity at the amino acid level. There are two closely related Napsins, napsin A and napsin B, with 85% overall identity at the amino acid level. There are three isoforms. Napsin-A is also termed napsin-1, or TA02, a Tumor Adenocarcinoma marker. Napsin A may be involved in processing of pneumocyte surfactant precursors.
Bioinformatics
Uniprot |
Human Human Human Human |
Product By Gene ID |
9476 |
Alternate Names |
- Asp 4
- ASP4
- Aspartyl protease 4
- EC 3.4.23
- EC 3.4.23.-
- EC 3.4.23.15
- EC 3.4.23.3
- EC 3.4.23.5
- KAP
- Kdap
- NAP1napsin-A
- NAPApronapsin A
- NAPSA
- napsin A aspartic peptidase
- napsin-1
- Napsin-1
- SNAPA
- TA01/TA02
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