MED17 Antibody (4D4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using H00009440-M01	Applications	Species
Kikuchi Y, Umemura H, Nishitani S et al. Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries. Genes Cells. 2014-12-07 [PMID: 25482373]
Tsutsui T, Fukasawa R, Tanaka A et al. Identification of target genes for the CDK subunits of the Mediator complex. Genes Cells. 2011-11-27 [PMID: 22117896]

Array H00009440-M01

• MED17 Antibodies
• MED17 Lysate
• MED17 Proteins