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MCM3 Antibody [DyLight 350]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-289AF350
Alexa Fluor 405
NB100-289AF405
Alexa Fluor 488
NB100-289AF488
Alexa Fluor 532
NB100-289AF532
Alexa Fluor 594
NB100-289AF594
Alexa Fluor 647
NB100-289AF647
Alexa Fluor 700
NB100-289AF700
Alexa Fluor 750
NB100-289AF750
Allophycocyanin
NB100-289APC
Biotin
NB100-289B
CoraFluor 1
NB100-289CL1
DyLight 405
NB100-289V
DyLight 488
NB100-289G
DyLight 550
NB100-289R
DyLight 594
NB100-289DL594
DyLight 650
NB100-289C
DyLight 680
NB100-289FR
DyLight 755
NB100-289IR
FITC
NB100-289F
HRP
NB100-289H
Janelia Fluor 525
NB100-289JF525
Janelia Fluor 549
NB100-289JF549
Janelia Fluor 585
NB100-289JF585
Janelia Fluor 635
NB100-289JF635
Janelia Fluor 646
NB100-289JF646
Janelia Fluor 669
NB100-289JF669
PE
NB100-289PE
PerCP
NB100-289PCP
Unconjugated
NB100-289
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MCM3 Antibody [DyLight 350] Summary

Immunogen
A 38-amino acid synthetic peptide, which represented a portion of human Minichromosome Maintenance Deficient 3 encoded in part by exons 10 and 11 (LocusLink ID 4172).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MCM3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MCM3 Antibody [DyLight 350]

  • cervical cancer proto-oncogene 5
  • DNA polymerase alpha holoenzyme-associated protein P1
  • DNA replication factor MCM3
  • DNA replication licensing factor MCM3
  • EC 3.6.4.12
  • HCC5
  • hRlf beta subunit
  • MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)
  • MCM3 minichromosome maintenance deficient 3
  • MGC1157
  • minichromosome maintenance complex component 3
  • minichromosome maintenance deficient (S. cerevisiae) 3
  • minichromosome maintenance deficient 3
  • P1.h
  • p102
  • P1-MCM3
  • replication licensing factor, beta subunit
  • RLF subunit beta
  • RLFB

Background

MCM3 is encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MCM3 Antibody
[DyLight 350]
NB100-289UV
MCM3 Antibody [DyLight 350]
Species: Hu, Mu
Applications: IHC, IP

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Bioinformatics

Gene Symbol MCM3