Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu, Mu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
MCM3 is encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
4172 |
| Alternate Names |
- cervical cancer proto-oncogene 5
- DNA polymerase alpha holoenzyme-associated protein P1
- DNA replication factor MCM3
- DNA replication licensing factor MCM3
- EC 3.6.4.12
- HCC5
- hRlf beta subunit
- MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)
- MCM3 minichromosome maintenance deficient 3
- MGC1157
- minichromosome maintenance complex component 3
- minichromosome maintenance deficient (S. cerevisiae) 3
- minichromosome maintenance deficient 3
- P1.h
- p102
- P1-MCM3
- replication licensing factor, beta subunit
- RLF subunit beta
- RLFB
|
