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MCM3 Antibody (MCM3/6706) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
MCM3/6706
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-24078AF350
Alexa Fluor 405
NBP3-24078AF405
Alexa Fluor 488
NBP3-24078AF488
Alexa Fluor 532
NBP3-24078AF532
Alexa Fluor 594
NBP3-24078AF594
Alexa Fluor 647
NBP3-24078AF647
Alexa Fluor 700
NBP3-24078AF700
Alexa Fluor 750
NBP3-24078AF750
Allophycocyanin
NBP3-24078APC
Biotin
NBP3-24078B
CoraFluor 1
NBP3-24078CL1
DyLight 350
NBP3-24078UV
DyLight 405
NBP3-24078V
DyLight 488
NBP3-24078G
DyLight 594
NBP3-24078DL594
DyLight 650
NBP3-24078C
DyLight 680
NBP3-24078FR
DyLight 755
NBP3-24078IR
FITC
NBP3-24078F
HRP
NBP3-24078H
Janelia Fluor 525
NBP3-24078JF525
Janelia Fluor 549
NBP3-24078JF549
Janelia Fluor 585
NBP3-24078JF585
Janelia Fluor 635
NBP3-24078JF635
Janelia Fluor 646
NBP3-24078JF646
Janelia Fluor 669
NBP3-24078JF669
PE
NBP3-24078PE
PerCP
NBP3-24078PCP
Unconjugated
NBP3-24078
mFluor Violet 450 SE
NBP3-24078MFV450
mFluor Violet 500 SE
NBP3-24078MFV500
mFluor Violet 610 SE
NBP3-24078MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-24078
Azide and BSA Free
NBP3-24078
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MCM3 Antibody (MCM3/6706) [DyLight 550] Summary

Immunogen
Recombinant fragment (aa 650-750) of human MCM3 protein (exact sequence is proprietary)
Localization
Nucleus.
Marker
Proliferation Marker
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MCM3
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MCM3 Antibody (MCM3/6706) [DyLight 550]

  • cervical cancer proto-oncogene 5
  • DNA polymerase alpha holoenzyme-associated protein P1
  • DNA replication factor MCM3
  • DNA replication licensing factor MCM3
  • EC 3.6.4.12
  • HCC5
  • hRlf beta subunit
  • MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)
  • MCM3 minichromosome maintenance deficient 3
  • MGC1157
  • minichromosome maintenance complex component 3
  • minichromosome maintenance deficient (S. cerevisiae) 3
  • minichromosome maintenance deficient 3
  • P1.h
  • p102
  • P1-MCM3
  • replication licensing factor, beta subunit
  • RLF subunit beta
  • RLFB

Background

MCM3 is encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MCM3 Antibody
(MCM3/6706) [DyLight
NBP3-24078R
MCM3 Antibody (MCM3/6706) [DyLight 550]
Species: Hu
Applications: IHC

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Bioinformatics

Gene Symbol MCM3