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Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-06640AF350
Alexa Fluor 405
NBP1-06640AF405
Alexa Fluor 488
NBP1-06640AF488
Alexa Fluor 532
NBP1-06640AF532
Alexa Fluor 594
NBP1-06640AF594
Alexa Fluor 647
NBP1-06640AF647
Alexa Fluor 700
NBP1-06640AF700
Alexa Fluor 750
NBP1-06640AF750
Allophycocyanin
NBP1-06640APC
Biotin
NBP1-06640B
CoraFluor 1
NBP1-06640CL1
DyLight 350
NBP1-06640UV
DyLight 405
NBP1-06640V
DyLight 488
NBP1-06640G
DyLight 550
NBP1-06640R
DyLight 594
NBP1-06640DL594
DyLight 650
NBP1-06640C
DyLight 680
NBP1-06640FR
DyLight 755
NBP1-06640IR
FITC
NBP1-06640F
HRP
NBP1-06640H
Janelia Fluor 525
NBP1-06640JF525
Janelia Fluor 549
NBP1-06640JF549
Janelia Fluor 585
NBP1-06640JF585
Janelia Fluor 635
NBP1-06640JF635
Janelia Fluor 646
NBP1-06640JF646
PE
NBP1-06640PE
PerCP
NBP1-06640PCP
Unconjugated
NBP1-06640
mFluor Violet 450 SE
NBP1-06640MFV450
mFluor Violet 500 SE
NBP1-06640MFV500
mFluor Violet 610 SE
NBP1-06640MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-06640
BSA Free
NBP1-06640
BSA Free
NBP1-06640SS
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Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [Janelia Fluor® 669] Summary

Immunogen
Synthetic peptide made to an internal portion of the mouse JMJD3 protein (within residues 600-650). [Swiss-Prot# Q5NCY0]
Localization
Nucleus
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KDM6B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [Janelia Fluor® 669]

  • EC 1.14.11
  • EC 1.14.11.-
  • JmjC domain-containing protein 3
  • JMJD3
  • JMJD3lysine-specific demethylase 6B
  • jumonji domain containing 3, histone lysine demethylase
  • Jumonji domain-containing protein 3
  • KDM6B
  • KIAA0346jumonji domain containing 3
  • Lysine (K)specific Demethylase 6B
  • Lysine (K)-specific Demethylase 6B
  • Lysine demethylase 6B

Background

JMJD3 is a histone demethylase that specifically demethylates trimethylated and dimethylated 'Lys-27' of histone H3, thereby playing a central role in histone code. JMJD3 is also important for the regulation of posterior development by regulating HOX gene expression. JMJD3 is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. It has also been shown to be essential to mammalian epidermal differentiation and is upregulated in prostate cancer.

JMJD3 antibodies are useful tools for epigenetics research and specifically for histone modification studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody (NBP1-06640JF669) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol KDM6B