Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody (7H3D7) - BSA Free Summary
Immunogen |
Purified recombinant fragment of human Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B (AA: 231-319) expressed in E. Coli. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
KDM5B |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- ELISA 1:10000
- Flow Cytometry 1:200-1:400
- Western Blot 1:500-1:2000
|
Application Notes |
This antibody is Cytof ready. |
Theoretical MW |
175.6 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.05% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Protein G purified |
Alternate Names for Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody (7H3D7) - BSA Free
Background
JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer. Alternative names for JARID1B include retinoblastoma-binding protein 2 homolog 1, RBP2-H1, cancer/testis antigen 31, CT31, PLU-1, PUT1, and KDM5B.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody (NBP2-52500) (0)
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Product General Protocols
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FAQs for Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody (NBP2-52500) (0)
Secondary Antibodies
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Isotype Controls
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