LYAG/GAA Antibody

GAA is acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
Enlarge	3 reviewed by: Pierre Jean Beltran	ICC	Human	04/05/2017	View Summary Application Immunocytochemistry Sample Tested Human fibroblast Species Human Lot QC14285-42033 Comments Comments LYAG was probed in human fibroblasts fixed with 4% PFA. Cells were permeabilized and blocked in 0.1% Tween and 1% Bovine serum albumin. Anti-LYAG was incubated overnight at 4C in PBS with 0.1% Tween and 1% Bovine serum albumin. Secondary antibody was anti-rabbit conjugated to Alexa Fluor 568. LYAG is shown in green and the nucleus in blue (Hoescht stain). Overall, the anitibody gave good signal, but with a significantly high cell-specific background as evident by some nuclear stain.

Array NBP1-69295

• LYAG/GAA Antibodies
• LYAG/GAA ELISA Kits
• LYAG/GAA Kit
• LYAG/GAA Lysates
• LYAG/GAA Proteins
• LYAG/GAA Proteins and Enzymes