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LAIR1 Antibody (NKTA255) [DyLight 650]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IP
Clone
NKTA255
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-62214AF350
Alexa Fluor 405
NBP2-62214AF405
Alexa Fluor 488
NBP2-62214AF488
Alexa Fluor 532
NBP2-62214AF532
Alexa Fluor 594
NBP2-62214AF594
Alexa Fluor 647
NBP2-62214AF647
Alexa Fluor 700
NBP2-62214AF700
Alexa Fluor 750
NBP2-62214AF750
Allophycocyanin
NBP2-62214APC
Biotin
NBP2-62214B
CoraFluor 1
NBP2-62214CL1
DyLight 350
NBP2-62214UV
DyLight 405
NBP2-62214V
DyLight 488
NBP2-62214G
DyLight 550
NBP2-62214R
DyLight 594
NBP2-62214DL594
DyLight 680
NBP2-62214FR
DyLight 755
NBP2-62214IR
FITC
NBP2-62214F
HRP
NBP2-62214H
Janelia Fluor 525
NBP2-62214JF525
Janelia Fluor 549
NBP2-62214JF549
Janelia Fluor 646
NBP2-62214JF646
Janelia Fluor 669
NBP2-62214JF669
PE
NBP2-62214PE
PerCP
NBP2-62214PCP
Unconjugated
NBP2-62214
mFluor Violet 450 SE
NBP2-62214MFV450
mFluor Violet 500 SE
NBP2-62214MFV500
mFluor Violet 610 SE
NBP2-62214MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-62214
BSA Free
NBP2-62214
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LAIR1 Antibody (NKTA255) [DyLight 650] Summary

Additional Information
Clone NKTA255 was used by HLDA to establish CD designation.
Immunogen
Activated NK cells and CD3- thymocytes
Specificity
The mouse monoclonal antibody NKTA255 recognizes CD305 / LAIR1, a 40 kDa type I transmembrane glycoprotein expressed on NK, T, and B cells, monocytes, dendritic cells, eosinophils, basophils, mast cells, CD34+ hematopoietic progenitor cells and thymocytes.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LAIR1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for LAIR1 Antibody (NKTA255) [DyLight 650]

  • CD305 antigen
  • CD305
  • CD305leukocyte-associated Ig-like receptor 1
  • HLAIR1
  • LAIR1
  • LAIR-1
  • leukocyte-associated immunoglobulin-like receptor 1

Background

LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LAIR1