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Kv7.1 Antibody [Janelia Fluor® 585]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-97900JF585
    • Availability
      Product Discontinued

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Kv7.1 Antibody [Janelia Fluor® 585] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human Kv7.1 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNQ1
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Kv7.1 Antibody [Janelia Fluor® 585]

  • ATFB3
  • IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1
  • JLNS1
  • KCNA8
  • KCNA8FLJ26167
  • KCNA9
  • KCNA9Kv1.9
  • KCNQ1
  • kidney and cardiac voltage dependend K+ channel
  • KQT-like 1
  • Kv7.1
  • KVLQT1
  • KVLQT1ATFB1
  • LQT
  • LQT1
  • potassium voltage-gated channel subfamily KQT member 1
  • potassium voltage-gated channel, KQT-like subfamily, member 1
  • RWS
  • slow delayed rectifier channel subunit
  • SQT2
  • Voltage-gated potassium channel subunit Kv7.1
  • WRS

Background

KCNQ1 encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. The gene is located in a region of chromosome 11 that contains a large number of contiguous genes that are abnormally imprinted in cancer and the Beckwith-Wiedemann syndrome. Two alternative transcripts encoding distinct isoforms have been described (from EntrezGene).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KCNQ1