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KLF17 Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: KLF17 Antibody [NBP1-81917] - Analysis in human testis and tonsil tissues. Corresponding KLF17 RNA-seq data are presented for the same tissues.
Western Blot: KLF17 Antibody [NBP1-81917] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with ...read more
Immunohistochemistry-Paraffin: KLF17 Antibody [NBP1-81917] - Staining of human tonsil shows low expression as expected.
Immunohistochemistry-Paraffin: KLF17 Antibody [NBP1-81917] - Staining of human pancreas shows no nuclear positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: KLF17 Antibody [NBP1-81917] - Staining of human skeletal muscle shows no nuclear positivity in myocytes as expected.
Immunohistochemistry-Paraffin: KLF17 Antibody [NBP1-81917] - Staining of human testis shows strong nuclear positivity in spermatids.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

KLF17 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: TVPSTEAQAVLPSMAQMLPPQDAHDLGMPPAESQSLLVLGSQDSLVSQPDSQEGPFLPEQPGPAPQTVEKNSRPQEGTG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KLF17
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
IHC reported in scientific literature (PMID: 26293300). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
KLF17 Protein (NBP1-81917PEP)
Publications
Read Publication using
NBP1-81917 in the following applications:

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 26293300).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for KLF17 Antibody

  • FLJ40160
  • KLF17
  • Kruppel-like factor 17
  • Zfp393
  • Zinc finger protein 393Krueppel-like factor 17
  • ZNF393
  • ZNF393novel zinc-finger protein

Background

Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as anegative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression.May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocytedevelopment

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KLF17 Antibody (NBP1-81917)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.


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IF/IHC
(1)
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Human
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol KLF17