Novus Biologicals products are now on bio-techne.com

KCNMB4 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: KCNMB4 Antibody [NBP2-56583] - Staining of human cell line RT4 shows localization to cytosol. Antibody staining is shown in green.
Orthogonal Strategies: Immunohistochemistry-Paraffin: KCNMB4 Antibody [NBP2-56583] - Staining in human cerebral cortex and pancreas tissues using anti-KCNMB4 antibody. Corresponding KCNMB4 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: KCNMB4 Antibody [NBP2-56583] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: KCNMB4 Antibody [NBP2-56583] - Staining of human pancreas shows low expression as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

KCNMB4 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: CWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQV
Predicted Species
Mouse (96%), Rat (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNMB4
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
KCNMB4 Recombinant Protein Antigen (NBP2-56583PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for KCNMB4 Antibody

  • BK channel subunit beta-4
  • BKbeta4
  • calcium-activated potassium channel subunit beta-4
  • Calcium-activated potassium channel, subfamily M subunit beta-4
  • Charybdotoxin receptor subunit beta-4
  • hbeta4
  • k(VCA)beta-4
  • large conductance calcium-dependent potassium ion channel beta 4 subunit
  • Maxi K channel subunit beta-4
  • potassium large conductance calcium-activated channel, subfamily M, beta member4
  • slo-beta-4

Background

KCNMB4, also known as Calcium-activated potassium channel subunit beta-4, is a 210 amino acid protein that is 34 kDa; predominantly expressed in brain; regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channels which are fundamental to the control of smooth muscle tone and neuronal excitability; is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. Current research is being pursued on this protein involvement in several diseases and disorders including neurological disorder, corpus callosum, epilepsy syndrome, seizures, neuronitis, and cerebritis. This protein has been linked to the hemostasis, potassium channels, Ca2+ activated K+ channels, cGMP effects, platelet homeostasis, synaptic transmission- ion currents, and vascular smooth muscle contraction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-87781
Species: Hu
Applications: IHC, IHC-P, WB
NB300-535
Species: Ca, Hu, Mu, Po, Rb, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, KD, WB
NBP2-12916
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, MiAr, WB
NBP2-12917
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, MiAr, WB
AF640
Species: Mu
Applications: IHC, WB
NBP1-86893
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NB100-755
Species: Hu, Mu
Applications: IHC, IHC-P, IP, KD, WB
NBP2-01526
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NBP3-05611
Species: Rt
Applications: ELISA, WB
NBP3-05611
Species: Rt
Applications: ELISA, WB
NBP3-12487
Species: Hu, Mu, Rt
Applications: ELISA, IHC, IHC-P, WB
NBP2-13304
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NB200-305
Species: Hu, Pm, Mu
Applications: ChIP, DB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
H00005729-B01P
Species: Hu
Applications: Flow, ICC/IF, WB
NBP1-89522
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP2-33694
Species: Hu
Applications: ICC/IF, IHC, IHC-P

Publications for KCNMB4 Antibody (NBP2-56583) (0)

There are no publications for KCNMB4 Antibody (NBP2-56583).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for KCNMB4 Antibody (NBP2-56583) (0)

There are no reviews for KCNMB4 Antibody (NBP2-56583). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for KCNMB4 Antibody (NBP2-56583) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our KCNMB4 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol KCNMB4