Jumonji/JARID2 Antibody (674702) Summary
Immunogen |
E. coli-derived recombinant human Jumonji/JARID2 Met1-Thr159 Accession # Q92833 |
Specificity |
Detects human Jumonji/JARID2 in direct ELISAs. |
Source |
N/A |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
JARID2 |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry 8-25 ug/mL
|
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Reconstitution Instructions |
Sterile PBS to a final concentration of 0.5 mg/mL. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Jumonji/JARID2 Antibody (674702)
Background
JARID2 (Jumonji/ARID domain-containing protein 2; also Jumonji [Japanese for “cruciform/cross”] and JMJ) is a 150-160 kDa member of the JMJ family of proteins. It is a nuclear complex coordinator that interacts with the G9a and GLP methyltransferases to repress gene transcription. JARID2 is expressed in mammalian embryonic neurons, megakaryocytes, hepatocytes and cardiomyocytes. Human JARID2 is 1246 amino acids (aa) in length. It contains an NLS (aa 1-131), a transcriptional repressor domain (aa 132-222), a DNA binding region (aa 558-709) and a nonfunctional histone demethylase domain (aa 916-1042). There are potential splice variants. One shows an alternative start site at Met173, another shows a deletion of aa 304-1151, and a third contains a 22 aa substitution for aa 1-60, coupled to a 50 aa substitution for aa 949-1246. Over aa 1-159, human JARID2 shares 96% aa identity with mouse JARID2.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Pm, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
Species: Hu, I, Mu, Rt, Xp, Ye
Applications: ChIP, IB, ICC/IF, IHC, IHC-P, Single-Cell Western, WB
Species: Hu, Mu
Applications: ICC, WB
Species: Hu
Applications: IHC, WB
Species: Hu
Applications: IHC
Species: Hu
Applications: ICC, Simple Western, WB
Species: Hu, Mu
Applications: IP, WB
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
Species: Hu, Mu
Applications: ChIP, ICC, IP, Simple Western, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu
Applications: ICC, IP, WB
Species: Hu, Mu
Applications: IHC, IHC-P, WB
Species: Hu
Applications: ELISA, ICC/IF, WB
Species: Hu, Mu
Applications: Flow, ICC/IF, IHC, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ICC/IF
Publications for Jumonji/JARID2 Antibody (MAB6090) (0)
There are no publications for Jumonji/JARID2 Antibody (MAB6090).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for Jumonji/JARID2 Antibody (MAB6090) (0)
There are no reviews for Jumonji/JARID2 Antibody (MAB6090).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
FAQs for Jumonji/JARID2 Antibody (MAB6090) (0)
Secondary Antibodies
| |
Isotype Controls
|
Additional Jumonji/JARID2 Products
Blogs on Jumonji/JARID2