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Integrin alpha 8 Antibody (481709) [Allophycocyanin]

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H4 human neuroglioma cell line was stained with Mouse Anti-Human Integrin a8 APC-conjugated Monoclonal Antibody (Catalog # FAB6194A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
481709
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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Integrin alpha 8 Antibody (481709) [Allophycocyanin] Summary

Immunogen
E. coli-derived recombinant human Integrin alpha 8
Glu610-Leu800
Accession # P53708
Specificity
Detects human Integrin alpha 8 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ITGA8
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha 8 Antibody (481709) [Allophycocyanin]

  • Integrin alpha 8
  • integrin alpha-8
  • integrin, alpha 8
  • ITGA8

Background

Integrin alpha 8 is a 170-200 kDa member of the Integrin family of adhesion molecules. It forms an exclusive noncovalent heterodimer with Integrin beta 1. Integrin alpha 8/ beta 1 promotes both cell adhesion and survival, and is known to bind to fibronectin, LAP-TGF beta 1 and Nephronectin. It is principally expressed in smooth muscle cells.  Human alpha 8 is a 1025 amino acid (aa) type I transmembrane glycoprotein. It contains a 974 aa extracellular domain (ECD) (aa 39-1012) and a 30 aa cytoplasmic domain. In the ECD, human alpha 8 shares 90% aa sequence identity with mouse alpha 8 protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ITGA8
Uniprot