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ILT5/CD85a/LILRB3 Antibody (222821) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
222821
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

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ILT5/CD85a/LILRB3 Antibody (222821) [DyLight 405] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LILRB3/CD85a/ILT5
Gly24-Glu443
Accession # AAB68668
Specificity
Detects human LILRB3/CD85a/ILT5 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT1, rhILT2, rhILT3, rhILT4, rhILT6, rhILT7 or rhILT11 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
LILRB3
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ILT5/CD85a/LILRB3 Antibody (222821) [DyLight 405]

  • CD85 antigen-like family member A
  • CD85a antigen
  • CD85a
  • HL9Immunoglobulin-like transcript 5
  • ILT5
  • ILT-5
  • ILT5CD85a
  • Leukocyte immunoglobulin-like receptor 3
  • leukocyte immunoglobulin-like receptor subfamily B member 3
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)
  • LILRB3
  • LIR3
  • LIR3CD85A
  • LIR-3MGC138403
  • member 3
  • Monocyte inhibitory receptor HL9
  • PIRB

Background

LILRB3 is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signaling modulators and inhibitors of cell activation. LILRB3 may act as receptor for class I MHC antigens.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LILRB3