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HYAL2 Antibody

Images

 
Immunohistochemistry-Paraffin: HYAL2 Antibody [NBP1-81283] - Staining of human liver shows weak positivity in a small subset of hepatocytes.
Immunohistochemistry-Paraffin: HYAL2 Antibody [NBP1-81283] - Staining of human kidney shows strong granular cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: HYAL2 Antibody [NBP1-81283] - Staining of human testis shows weak to moderate cytoplasmic positivity in peritubular myoid cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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HYAL2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: APPIFTGRPFVVAWDVPTQDCGPRLKVPLDLNAFDVQASPNEGFVNQNITIFYRDRLGLYPRFDSAGRSVHGGVPQNVSLWAHRK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HYAL2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
HYAL2 Protein (NBP1-81283PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%), Rat (80%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HYAL2 Antibody

  • EC 3.2.1.35
  • HYAL-2
  • Hyaluronidase 2
  • hyaluronoglucosaminidase 2
  • hyaluronoglucosaminidase-2
  • LUCA2
  • LUCA-2
  • LUCA2hyaluronidase-2
  • Lung carcinoma protein 2
  • lysosomal hyaluronidase
  • PH20 homolog
  • PH-20 homolog

Background

HYAL2 (Hyaluronoglucosaminidase 2) is involved in glycosaminoglycan catabolism. HYAL2 has been associated with tumor suppression due to its location in a region of chromosome 3p21.3. HYAL2 is known to have interactions with MST1R, ERVW-1, ARSB, CD44 and HMMR. HYAL2 has been studied in relation to several diseases and disorders including lung carcinoma, breast cancer, COPD, gastric cancer, endometrial cancer, Non-Hodgkin lymphoma, rheumatoid arthritis, Hodgkin's lymphoma and osteoarthritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HYAL2