Human Mesothelin Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Mesothelin, also known as CAK1 and ERC, is derived from a precursor that also includes Megakaryocyte Potentiating Factor (MPF). Following cleavage of the precursor, Mesothelin remains attached to the cell surface via a GPI linkage. Mesothelin is normally expressed on mesothelial cells in the pleura, pericardium, and peritoneum as well as in the developing and postnatal pancreas. It is upregulated in mesotheliomas and a range of carcinomas and adenomas. Mesothelin promotes tumor cell proliferation, migration, anchorage-independent growth, and tumor progression.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 3 of 3.

Publications using DMSLN0	Applications	Species
X Zhang, Y Yu, CJ Peer, R Landsman, N Skorupan, L Cao, C Alewine Low serum mesothelin in pancreatic cancer patients results from retention of shed mesothelin in the tumor microenvironment Translational Oncology, 2022-05-04;21(0):101440. 2022-05-04 [PMID: 35523008] (Human)		Human
S Casjens, DG Weber, G Johnen, I Raiko, D Taeger, C Meinig, S Moebus, KH Jöckel, T Brüning, B Pesch Assessment of potential predictors of calretinin and mesothelin to improve the diagnostic performance to detect malignant mesothelioma: results from a population-based cohort study BMJ Open, 2017-10-11;7(10):e017104. 2017-10-11 [PMID: 29025836] (Human)		Human
Chen Y, Ayaru L, Mathew S, Morris E, Pereira S, Behboudi S Expansion of anti-mesothelin specific CD4+ and CD8+ T cell responses in patients with pancreatic carcinoma. PLoS ONE, 2014-02-10;9(2):e88133. 2014-02-10 [PMID: 24520352] (Human)		Human

Array DMSLN0

• Mesothelin Antibodies
• Mesothelin Lysate
• Mesothelin Protein
• Mesothelin Proteins and Enzymes
• Mesothelin ELISAs