Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human CA125/MUC16 DuoSet ELISA, 5 Plate
CA125 ovarian cancer antigen
CA125
CA-125
CA125MUC-16
FLJ14303
MUC16
mucin 16, cell surface associated
mucin-16
Ovarian cancer-related tumor marker CA125
Ovarian carcinoma antigen CA125
Background
The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.