HSPA8/HSC71/Hsc70 Antibody (1D9)

The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Plant, Porcine.

We have publications tested in 1 application: WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-97498	Applications	Species
K Hirschi et al. AtCCX3 Is an Arabidopsis Endomembrane H(+)-Dependent K(+) Transporter. Plant Physiol. 148, 1474 . 2008-01-01 [PMID: 18775974] (WB, Porcine)	WB	Porcine
KD Hirschi et al. The Arabidopsis cax1 mutant exhibits impaired ion homeostasis, development, and hormonal responses and reveals interplay among vacuolar transporters. Plant Cell 15, 347 . 2003-01-01 [PMID: 12566577] (WB, Plant)	WB	Plant
E Lam et al. Mechanism of cell death and disease resistance induction by transgenic expression of bacterio-opsin. Plant J. 30, 499 . 2002-01-01 [PMID: 12047625] (WB, Plant)	WB	Plant

Array NBP1-97498

• HSPA8/HSC71/Hsc70 Antibodies
• HSPA8/HSC71/Hsc70 ELISA Kits
• HSPA8/HSC71/Hsc70 Lysate
• HSPA8/HSC71/Hsc70 Protein