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HERV Antibody

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Western Blot: HERV Antibody [NBP2-86666] - Host: Rabbit. Target Name: ERVW-1. Sample Type: HT1080 Whole Cell lysates. Antibody Dilution: 1.0ug/ml
Western Blot: HERV Antibody [NBP2-86666] - Host: Rabbit. Target: ERVW-1. Positive control (+): Human Placenta (PL). Negative control (-): 293T (2T). Antibody concentration: 1ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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HERV Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human HERV. Peptide sequence: CMTSSSPYQEFLWRMQRPGNIDAPSYRSLSKGTPTFTAHTHMPRNCYHSA The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
ERVW-1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for HERV Antibody

  • endogenous retroviral family W, env(C7), member 1
  • ENV
  • envelope glycoprotein
  • Envelope polyprotein gPr73
  • enverin
  • ENVW
  • Env-W
  • HERV-7q Envelope protein
  • HERV7Q
  • HERV-7q
  • HERV-tryptophan envelope protein
  • HERV-W Env glycoprotein
  • HERV-W envelope protein
  • HERV-W
  • HERV-W_7q21.2 provirus ancestral Env polyprotein
  • HERV-W{7q21.1} provirus ancestral Env polyprotein
  • HERVWENV
  • HERV-W-ENV
  • HERVWenvelope protein
  • human endogenous retrovirus W envC7-1 envelope protein
  • syncytin A
  • Syncytin
  • syncytin-1

Background

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional HERV Products

Array NBP2-86666

Research Areas for HERV Antibody (NBP2-86666)

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Blogs on HERV

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Bioinformatics

Gene Symbol ERVW-1