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HAND2 Antibody [Biotin]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
AF3876
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
AF3876
Carrier Free
AF3876
Carrier Free
AF3876-SP
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HAND2 Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant human HAND2
Met1-Gln217
Accession # P61296
Specificity
Detects human and mouse HAND2 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human HAND1 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
HAND2
Purity Statement
Antigen Affinity-purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Readout System

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HAND2 Antibody [Biotin]

  • BHLHA26
  • bHLHa26MGC125303
  • dHand
  • DHAND2
  • Ehand2
  • FLJ16260
  • HAND2
  • heart and neural crest derivatives expressed 2
  • heart, autonomic nervous system and neural crestderivatives-expressed protein 2
  • Hed
  • MGC125304
  • Th2
  • Thing2

Background

HAND2 (also known as dHAND, Thing-2 and Hed) is a 24 kDa, class B member of the basic helix-loop-helix transcription factors superfamily. HAND2 is essential for cardiac morphogenesis and required for vascular development and regulation of angiogenesis, possibly through VEGF signaling. HAND2 is also implicated in limb development acting as an upstream regulator of sonic hedgehog. Alternative initiation and internal deletions result in at least three potential HAND2 isoforms. Human and mouse HAND2 proteins are 100% identical.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HAND2
Uniprot