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HAI-2/SPINT2 Antibody (RM0089-7F52) - Azide and BSA Free

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Immunohistochemistry-Paraffin: HAI-2/SPINT2 Antibody (RM0089-7F52) [NBP1-21728] - The Kidney tissue samples from the Folic Acid induced kidney injury model were fixed using 4% PFA at 4C for overnight and embeded in ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC
Clone
RM0089-7F52
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
LYOPH

Order Details

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HAI-2/SPINT2 Antibody (RM0089-7F52) - Azide and BSA Free Summary

Immunogen
Mouse recombinant of the common extracellular region of HAI-2 isoforms
Specificity
This antibody detects mouse HIA-2, but not HAI-1 in Western blotting.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
SPINT2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified
Reconstitution Instructions
Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for HAI-2/SPINT2 Antibody (RM0089-7F52) - Azide and BSA Free

  • HAI2
  • HAI-2
  • HAI-2DIAR3
  • HAI2FLJ45571
  • Hepatocyte growth factor activator inhibitor type 2
  • Kop
  • kunitz-type protease inhibitor 2
  • PB
  • Placental bikunin
  • serine peptidase inhibitor, Kunitz type, 2
  • serine protease inhibitor, Kunitz type, 2

Background

HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SPINT2
Entrez