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GUCY2F Antibody

Images

 
Western Blot: GUCY2F Antibody [NBP3-12219] - WB of NBP3-12219 pre-immune. 1:500 antibody dilution in diluobuffer. Apparent MW is 120 kDa.
Immunohistochemistry-Paraffin: GUCY2F Antibody [NBP3-12219] - Section of mouse retina. Red: Antibody immunoreactivity. Blue: Nuclei. Photoreceptor outer segments are labeled by NBP3-12219.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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GUCY2F Antibody Summary

Immunogen
Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase F protein.
Clonality
Polyclonal
Host
Rabbit
Gene
GUCY2F
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:10000
  • Immunocytochemistry/ Immunofluorescence 1:200
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for GUCY2F Antibody

  • CYGF
  • EC 4.6.1
  • GC-F
  • GC-FEC 4.6.1.2
  • guanylate cyclase 2F, retinalRETGC-2
  • Guanylate cyclase F
  • Guanylyl Cyclase F
  • GUC2DL
  • GUC2Fguanylate cyclase 2D-like, membrane (retina-specific)
  • GUCY2F
  • RETGC2
  • retinal guanylyl cyclase 2
  • Rod outer segment membrane guanylate cyclase 2
  • ROS-GC2
  • ROS-GC2RetGC-2

Background

The GUCY2F gene encodes a retinal guanylyl cyclase 2 single-pass type 1 membrane protein that plays a significant functional role in the rods and cones of photoreceptors. Its coded proteins are 1,108 amino acids long at a mass of approximately 124 kDA. It is thought to be involved in the resynthesis of cGMP which is required for recovery of a dark state after light activation of the visual signal transduction cascade (phototransduction). The GUCY2F gene participates is purine metabolism, relaxin pathway, phototransduction, and the CRHR pathway. Its known to interact with various genes such as GUCA1B, GUCA1A, GUCA1C, PDE11A, and PDE4A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GUCY2F