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GRK2 Antibody (S01-6I5)

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Western Blot: GRK2 Antibody (S01-6I5) [NBP3-20067] - Western blot detection of GRK2 in Hela, A549, HL-60, U2OS cell lysates using NBP3-20067 (1:1000 diluted). Predicted band size: 80kDa. Observed band size: 80kDa.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
S01-6I5
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.3 mg/ml

Order Details

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GRK2 Antibody (S01-6I5) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide of human GRK2 (Uniprot # P25098)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
GRK2
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1/1000
Theoretical MW
80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Concentration
0.3 mg/ml
Purity
Affinity purified

Alternate Names for GRK2 Antibody (S01-6I5)

  • ADRBK1
  • adrenergic, beta, receptor kinase 1
  • BARK
  • BARK1
  • BARK1beta-ARK-1
  • Beta-ARK1
  • Beta-ARK-1
  • EC 2.7.11
  • EC 2.7.11.15
  • FLJ16718
  • G-protein coupled receptor kinase 2
  • GRK2
  • GRK2beta-adrenergic receptor kinase 1

Background

Adrenergic Receptor beta Kinase 1 (ADRBK1), also known as GRK2, is a member of the G-protein receptor kinase family. A ubiquitous cytosolic enzyme, GRK-2 specifically phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed under high agonist concentrations. Defects in GRK2 coupling with G-protein receptors may lead to heart failure.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GRK2