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Gephyrin/GPHN Antibody (OTI3B6) [mFluor Violet 500 SE]

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Gephyrin/GPHN Antibody (OTI3B6) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.
Gephyrin/GPHN Antibody (OTI3B6) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.

Product Details

Summary
Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clone
OTI3B6
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 500 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-71556AF350
Alexa Fluor 405
NBP2-71556AF405
Alexa Fluor 488
NBP2-71556AF488
Alexa Fluor 532
NBP2-71556AF532
Alexa Fluor 594
NBP2-71556AF594
Alexa Fluor 647
NBP2-71556AF647
Alexa Fluor 700
NBP2-71556AF700
Alexa Fluor 750
NBP2-71556AF750
Allophycocyanin
NBP2-71556APC
Biotin
NBP2-71556B
CoraFluor 1
NBP2-71556CL1
DyLight 350
NBP2-71556UV
DyLight 405
NBP2-71556V
DyLight 488
NBP2-71556G
DyLight 550
NBP2-71556R
DyLight 594
NBP2-71556DL594
DyLight 650
NBP2-71556C
DyLight 680
NBP2-71556FR
DyLight 755
NBP2-71556IR
FITC
NBP2-71556F
HRP
NBP2-71556H
Janelia Fluor 525
NBP2-71556JF525
Janelia Fluor 549
NBP2-71556JF549
Janelia Fluor 646
NBP2-71556JF646
Janelia Fluor 669
NBP2-71556JF669
PE
NBP2-71556PE
PerCP
NBP2-71556PCP
Unconjugated
NBP2-03449
mFluor Violet 610 SE
NBP2-71556MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-03449
Azide and BSA Free
NBP2-71556
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Gephyrin/GPHN Antibody (OTI3B6) [mFluor Violet 500 SE] Summary

Immunogen
Full length human recombinant protein of human GPHN (NP_065857) produced in HEK293T cell.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GPHN
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Gephyrin/GPHN Antibody (OTI3B6) [mFluor Violet 500 SE]

  • GEPH
  • Gephyrin
  • GPH
  • GPHN
  • GPHRYN
  • KIAA1385GPHGEPH

Background

The Gephyrin (GPHN) gene encodes a neuronal assembly protein that exists in isoform 1 (736 amino acids long, 79 kDA) or isoform 2 (769 amino acids in length, approximately 83 kDA). This protein anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton through high affinity binding to a receptor subunit domain and tublin dimers. The protein coded by GPHN is also necessary for molybdenum biosynthesis. The GPHN gene has been investigated in relation to many diseases such as leukemia, cervicitis, tuberculosis, alzheimer's disease, anorexia nervosa, huntington's disease, retinitis, and herpes zoster. The GPHN gene interacts with genes DYNLL1, PFN1, PRPF4, ENAH, and SLX4 to participate in pathways that regulate metabolism of vitamins and cofactors as well as molybdenum cofactor biosynthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GPHN