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GADD34 Antibody

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Immunohistochemistry-Paraffin: GADD34 Antibody [NBP1-89800] - Staining of human pancreas shows strong cytoplasmic positivity in both exocrine glandular cells and islet cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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GADD34 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: QPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCP
Localization
Endoplasmic reticulum
Marker
ER Stress Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP1R15A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
IHC-P, Retrieval method: HIER pH6
Theoretical MW
74 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
GADD34 Protein (NBP1-89800PEP)
Publications
Read Publication using NBP1-89800.

Reactivity Notes

Use in Mouse reported in scientific publication (PMID: 32435966).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for GADD34 Antibody

  • GADD34
  • GADD34Growth arrest and DNA damage-inducible protein GADD34
  • growth arrest and DNA-damage-inducible 34
  • Myeloid differentiation primary response protein MyD116 homolog
  • PPP1R15A
  • protein phosphatase 1 regulatory subunit 15A
  • protein phosphatase 1, regulatory (inhibitor) subunit 15A

Background

GADD34 is a phosphatase whose expression is increased by exposure of cells to DNA damage or stress induced growth arrest. Induction is correlated with apoptosis following exposure to ionizing radiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GADD34 Antibody (NBP1-89800)(1)

We have publications tested in 1 confirmed species: Mouse.


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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PPP1R15A
Entrez
Uniprot