Recombinant Human G3BP1 His Protein

G3BP1 is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. And it cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. Recombinant human G3BP1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 2 applications: In vitro, WB.

Showing Publications 1 - 4 of 4.

Publications using NBP1-50925	Applications	Species
Yang T, Wang G, Zhang M et al. Triggering endogenous Z-RNA sensing for anti-tumor therapy through ZBP1-dependent necroptosis Cell reports 2023-11-02 [PMID: 37922310] (In vitro)	In vitro
Dong R, Li X, Flores AD, Lai KO The translation initiating factor eIF4E and arginine methylation underlie G3BP1 function in dendritic spine development of neurons The Journal of biological chemistry 2023-07-11 [PMID: 37442236] (In vitro)	In vitro
Sanders DW, Kedersha N, Lee DSW et al. Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization Cell 2020-04-16 [PMID: 32302570] (WB)	WB
Oi N, Yuan J, Malakhova M et al. Resveratrol induces apoptosis by directly targeting Ras-GTPase-activating protein SH3 domain-binding protein 1. Oncogene 2014-07-07 [PMID: 24998844] (In vitro)	In vitro

Array NBP1-50925

• G3BP1 Antibodies
• G3BP1 Lysates
• G3BP1 Proteins