Frizzled-6 Antibody Blocking Peptide Summary
Description |
A blocking peptide containing 14 amino acids in the central domain of human Frizzled-6. Source: Synthetic (Accession #: O60353) |
Source |
Synthetic |
Protein/Peptide Type |
Antibody Blocking Peptide |
Gene |
FZD6 |
Purity |
N/A |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NBP3-18335. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin. |
Preservative |
0.02% Sodium Azide |
Concentration |
0.2 mg/ml |
Purity |
N/A |
Alternate Names for Frizzled-6 Antibody Blocking Peptide
Background
FZD6 is a Frizzled Receptor for Wnt signaling proteins involved in patterning during development. Contrary to other Frizzled proteins, FZD6 does not contain a C-terminal PDZ domain-binding motif. FZD6 is widely expressed. The Drosophila homolog activates Dishevelled. FZD6 expression has been reported in brain, colon, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, testis, and thymus. Various tumor cell lines have also been shown to express FZD6. ESTs have been isolated from blood, brain, breast, connective tissue, liver, liver/spleen, lung, placenta, testis, thyroid, and vessel libraries. In addition, several ESTs have been isolated from tumor libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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