Name: ERR beta/NR3B2 Antibody (H6705) [Unconjugated]
Brand: Novus Biologicals
SKU: PP-H6705-00
Price: 479 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, IHC, IP
Clone	H6705
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated
Suitable Sample Type	23015

Source	N/A
Isotype	IgG2a
Clonality	Monoclonal
Host	Mouse
Gene	ESRRB
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer	A liquid formulation in physiologic saline with 0.1% NaN₃.
Preservative	0.1% Sodium Azide

Publications using PP-H6705-00	Applications	Species
Li, QS;Zheng, PS; ESRRB inhibits the TGF-? signaling pathway to drive cell proliferation in cervical cancer Cancer research 2023-06-23 [PMID: 37350664] (IHC, Western Blot, ChIP, Human)	IHC, Western Blot, ChIP	Human
Zhu, Z;Chen, X;Guo, A;Manzano, T;Walsh, PJ;Wills, KM;Halliburton, R;Radko-Juettner, S;Carter, RD;Partridge, JF;Green, DR;Zhang, J;Roberts, CWM; Mitotic bookmarking by SWI/SNF subunits Nature 2023-06-01 [PMID: 37225980] (Bioassay, ICC, Mouse)	Bioassay, ICC	Mouse
R Yelagandul, K Stecher, M Novatchkov, L Michetti, G Michlits, J Wang, P Hofbauer, G Vainorius, C Pribitzer, L Isbel, S Mendjan, D Schübeler, U Elling, J Brennecke, O Bell ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers Nature Cell Biology, 2023-01-05;0(0):. 2023-01-05 [PMID: 36604593] (ChIP, Mouse)	ChIP	Mouse
MN Khan, P Cherukuri, F Negro, A Rajput, P Fabrowski, V Bansal, C Lancelin, TI Lee, Y Bian, WP Mayer, T Akay, D Müller, S Bonn, D Farina, T Marquardt ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control PloS Biology, 2022-12-21;20(12):e3001923. 2022-12-21 [PMID: 36542664] (IHC, Human)	IHC	Human
Sapir Herchcovici Levy, Sharon Feldman Cohen, Lee Arnon, Shlomtzion Lahav, Muhammad Awawdy, Adi Alajem et al. Esrrb is a cell-cycle-dependent associated factor balancing pluripotency and XEN differentiation Stem Cell Reports 2022-06-01 [PMID: 35594859]
Daisuke Suzuki, Keitaro Okura, Seina Nagakura, Hidehiko Ogawa CDX2 downregulation in mouse mural trophectoderm during peri‐implantation is heteronomous, dependent on the YAP‐TEAD pathway and controlled by estrogen‐induced factors Reproductive Medicine and Biology 2022-02-27 [PMID: 35386376]
Kang-Xuan Jin, Rujuan Zuo, Konstantinos Anastassiadis, Arne Klungland, Carsten Marr, Adam Filipczyk N6-methyladenosine (m 6 A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells Proceedings of the National Academy of Sciences 2021-12-21 [PMID: 34921114]
J Bayerl, M Ayyash, T Shani, YS Manor, O Gafni, R Massarwa, Y Kalma, A Aguilera-C, M Zerbib, H Amir, D Sheban, S Geula, N Mor, L Weinberger, S Naveh Tass, V Krupalnik, B Oldak, N Livnat, S Tarazi, S Tawil, E Wildschutz, S Ashouokhi, L Lasman, V Rotter, S Hanna, D Ben-Yosef, N Novershter, S Viukov, JH Hanna Principles of signaling pathway modulation for enhancing human naive pluripotency induction Cell Stem Cell, 2021-04-28;0(0):. 2021-04-28 [PMID: 33915080] (ICC, Mouse)	ICC	Mouse
R Fan, YS Kim, J Wu, R Chen, D Zeuschner, K Mildner, K Adachi, G Wu, S Galatidou, J Li, HR Schöler, SA Leidel, I Bedzhov Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause Nat Commun, 2020-10-30;11(1):5499. 2020-10-30 [PMID: 33127892] (ICC, IHC, Mouse)	ICC, IHC	Mouse
Lior Lasman, Vladislav Krupalnik, Sergey Viukov, Nofar Mor, Alejandro Aguilera-Castrejon, Dan Schneir et al. Context-dependent functional compensation between Ythdf m6A reader proteins Genes & Development 2020-10-01 [PMID: 32943573]
Aurélia Huyghe, Giacomo Furlan, Duygu Ozmadenci, Christina Galonska, Jocelyn Charlton, Xavier Gaume et al. Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling Nature Cell Biology 2020-04-01 [PMID: 32231305]
Aileen I. Fernandez, Xue Geng, Krysta Chaldekas, Brent Harris, Anju Duttargi, V. Layne Berry et al. The orphan nuclear receptor estrogen-related receptor beta (ERR beta ) in triple-negative breast cancer Breast Cancer Research and Treatment 2020-02-01 [PMID: 31741180]
Garland W, Comet I, Wu M et al. A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2 Cell Rep 11/12/2019 [PMID: 31722198]
Hannah T. Stuart, Giuliano G. Stirparo, Tim Lohoff, Lawrence E. Bates, Masaki Kinoshita, Chee Y. Lim et al. Distinct Molecular Trajectories Converge to Induce Naive Pluripotency Cell Stem Cell 2019-09-05 [PMID: 31422912]
A Bahat, A Goldman, Y Zaltsman, DH Khan, C Halperin, E Amzallag, V Krupalnik, M Mullokando, A Silberman, A Erez, AD Schimmer, JH Hanna, A Gross MTCH2-mediated mitochondrial fusion drives exit from naï¿½ve pluripotency in embryonic stem cells Nat Commun, 2018-12-03;9(1):5132. 2018-12-03 [PMID: 30510213] (ICC, Human)	ICC	Human
JL Sardina, S Collombet, TV Tian, A Gómez, B Di Stefano, C Berenguer, J Brumbaugh, R Stadhouder, C Segura-Mor, M Gut, IG Gut, S Heath, S Aranda, L Di Croce, K Hochedling, D Thieffry, T Graf Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate Cell Stem Cell, 2018-09-13;0(0):. 2018-09-13 [PMID: 30220521] (Immunoprecipitation, Mouse)	Immunoprecipitation	Mouse
Amanda Andersson-Rolf, Roxana C. Mustata, Alessandra Merenda, Jihoon Kim, Sajith Perera, Tiago Grego et al. One-step generation of conditional and reversible gene knockouts Nature Methods 2017-03-01 [PMID: 28135257]
Daniel A Rappolee Departure from optimal O2 level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation J. Reprod. Dev., 2016-11-18;0(0):. 2016-11-18 [PMID: 27867161] (Western Blot, Mouse)	Western Blot	Mouse
Heckler MM, Zeleke TZ, Divekar SD et al. Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRb2) splice variant in breast cancer Oncotarget 7/26/2016 [PMID: 27363015]
Yuan Lu, Jilong Li, Jianlin Cheng, Dennis B. Lubahn Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells BMC Molecular Biology 2015-12-01 [PMID: 26627478]
Yuan Lu, Jilong Li, Jianlin Cheng, Dennis B. Lubahn Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor beta BMC Molecular Biology 2015-12-01 [PMID: 26597826]
Mary Mazzotta Heckler, Rebecca B Riggins ERR beta splice variants differentially regulate cell cycle progression Cell Cycle 2015-01-02 [PMID: 25496115]
Kumar , Roshan M, Cahan , Patrick, Shalek , Alex K, Satija , Rahul, DaleyKeyser , A Jay, Li , Hu, Zhang , Jin, Pardee , Keith, Gennert , David, Trombetta , John J, Ferrante , Thomas C, Regev , Aviv, Daley , George Q, Collins , James J Deconstructing transcriptional heterogeneity in pluripotent stem cells. Nature, 2014-12-04;516(7529):56-61. 2014-12-04 [PMID: 25471879] (IHC, Mouse)	IHC	Mouse
Félix Leroy, Boris Lamotte d'Incamps, Rebecca D Imhoff-Manuel, Daniel Zytnicki Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis eLife 2014-10-14 [PMID: 25313866]
Aliaksandra Radzisheuskaya, Gloryn Le Bin Le Bin Chia, Rodrigo L. dos Santos, Thorold W. Theunissen, L. Filipe C. Castro, Jennifer Nichols et al. A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages Nature Cell Biology 2013-06-01 [PMID: 23629142]
Percharde M, Lavial F, Ng J, Kumar V, Tomaz R, Martin N, Yeo J, Gil J, Prabhakar S, Ng H, Parker M, Azuara V Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming. Genes Dev, 2012-09-26;26(20):2286-98. 2012-09-26 [PMID: 23019124] (ICC, Mouse)	ICC	Mouse
van den Berg DL, Zhang W, Yates A, Engelen E, Takacs K, Bezstarosti K, Demmers J, Chambers I, Poot RA Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression. Mol. Cell. Biol., 2008-07-28;28(19):5986-95. 2008-07-28 [PMID: 18662995] (ICC, Human)	ICC	Human
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ERR beta/NR3B2 Antibody (H6705) [Unconjugated]

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