EphA3 Antibody (ifabotuzumab) - Chimeric Summary
Description |
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
Also known as 'ifabotuzumab'.
Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles. |
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
EphA3 |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Human |
Gene |
EPHA3 |
Purity |
Protein A purified |
Endotoxin Note |
< 0.001EU/ug,determined by LAL method. |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Flow Cytometry
- Functional
|
Packaging, Storage & Formulations
Storage |
Store at -20C in powder form. Store at -80C once reconstituted. |
Buffer |
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2) |
Preservative |
No Preservative |
Concentration |
LYOPH |
Purity |
Protein A purified |
Reconstitution Instructions |
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex. |
Alternate Names for EphA3 Antibody (ifabotuzumab) - Chimeric
Background
Eph receptor A3 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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