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Endothelin-1 Antibody (TR.ET.48.5) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Ca, Rb, ShSpecies Glossary
Applications WB, Flow, Func, ICC/IF, IHC
Clone
TR.ET.48.5
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB300-526AF350
Alexa Fluor 405
NB300-526AF405
Alexa Fluor 488
NB300-526AF488
Alexa Fluor 532
NB300-526AF532
Alexa Fluor 594
NB300-526AF594
Alexa Fluor 647
NB300-526AF647
Alexa Fluor 700
NB300-526AF700
Alexa Fluor 750
NB300-526AF750
Allophycocyanin
NB300-526APC
Biotin
NB300-526B
DyLight 350
NB300-526UV
DyLight 405
NB300-526V
DyLight 550
NB300-526R
DyLight 594
NB300-526DL594
DyLight 650
NB300-526C
DyLight 680
NB300-526FR
DyLight 755
NB300-526IR
FITC
NB300-526F
HRP
NB300-526H
Janelia Fluor 549
NB300-526JF549
Janelia Fluor 646
NB300-526JF646
PE
NB300-526PE
PerCP
NB300-526PCP
Unconjugated
NB300-526
mFluor Violet 450 SE
NB300-526MFV450
mFluor Violet 500 SE
NB300-526MFV500
mFluor Violet 610 SE
NB300-526MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB300-526
BSA Free
NB300-526
BSA Free
NB300-526-0.025ml
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Endothelin-1 Antibody (TR.ET.48.5) [DyLight 488] Summary

Immunogen
Pure endothelin-1 conjugated to KLH.
Epitope
Studies suggest that this antibody binds to an epitope in the region of ET-1 represented by amino acids 8-16.
Localization
Secreted
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
EDN1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Radioimmunoassay
  • Western Blot

Reactivity Notes

Canine reactivity reported in scientific literature (PMID: 11673223). Rabbit reactivity reported in scientific literature (PMID: 12181591). Porcine reactivity reported in scientific literature (PMID: 21587116). Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Endothelin-1 Antibody (TR.ET.48.5) [DyLight 488]

  • ARCND3
  • EDN1
  • endothelin 1
  • Endothelin-1
  • ET1
  • HDLCQ7
  • PPET1
  • preproendothelin-1
  • QME

Background

Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol EDN1
Entrez
Uniprot