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DR1 Antibody [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

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DR1 Antibody [Janelia Fluor® 525] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 25 and 75 of human down-regulator of transcription 1 using the numbering given in entry NP_001929.1 (GeneID 1810).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DR1 Antibody [Janelia Fluor® 525]

  • Down-regulator of transcription 1
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • NC2
  • NC2-BETA
  • Negative cofactor 2-beta
  • protein Dr1
  • TATA-binding protein-associated phosphoprotein

Background

DR1 encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional DR1 Products

Array NBP1-03329JF525

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Bioinformatics

Gene Symbol DR1