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DOCK11 Antibody [Janelia Fluor® 635]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 635

Order Details

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DOCK11 Antibody [Janelia Fluor® 635] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human dedicator of cytokinesis 11 using the numbering given in entry NP_653259.3 (GeneID 139818).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DOCK11
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DOCK11 Antibody [Janelia Fluor® 635]

  • ACG
  • Activated Cdc42-associated guanine nucleotide exchange factor
  • Activated Cdc42-associated guanine nucleotide exchange factor, ACG
  • bB128O4.1
  • bB128O4.1.1 (novel protein)
  • dedicator of cytokinesis 11
  • FLJ32122
  • FLJ43653
  • ZIZ2dedicator of cytokinesis protein 11
  • zizimin2
  • zizimin-2

Background

DOCK11 (dedicator of cytokinesis 11) is also known as zizimin-2. It is a DOCK180-related guanine nucleotide exchange factor (GEF) for the small GTPase, Cdc42. As a GEF, DOCK11 functions to catalyze the dissociation of GDP from the GTPase. Dissociation of GDP allows an exchange for GTP and subsequent downstream signaling by the GTPase. Alternate names for DOCK11 include activated Cdc42-associated guanine nucleotide exchange factor, ACG, and ZIZ2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DOCK11