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DDR1 Antibody (3E3) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, B/N
Clone
3E3
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 750

Order Details

DDR1 Antibody (3E3) [Alexa Fluor® 750] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant human DDR1 extracellular domain.
Specificity
This antibody binds specifically to the extracellular domain of human DDR1.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
DDR1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Block/Neutralize
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DDR1 Antibody (3E3) [Alexa Fluor® 750]

  • CAK
  • CD167 antigen-like family member A
  • CD167a antigen
  • CD167a
  • DDR
  • DDR1
  • discoidin domain receptor family, member 1
  • discoidin domain receptor tyrosine kinase 1
  • Discoidin receptor tyrosine kinase
  • EC 2.7.10
  • EC 2.7.10.1
  • EDDR1
  • ENTRK4
  • Epithelial discoidin domain receptor 1
  • HGK2
  • MCK10
  • MCK-10
  • NTRK4
  • Protein-tyrosine kinase 3A
  • PTK3A protein tyrosine kinase 3A
  • PTK3A
  • receptor, type 4
  • RTK6
  • TRK E
  • TrkE

Background

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for DDR1 Antibody (NBP2-81073AF750). (Showing 1 - 1 of 1 FAQ).

  1. I was wondering if you offer, or are planning on offering, any antibodies targeted to specific phosphorylation sites on the receptor tyrosine kinase DDR1.
    • At this time we do not offer and DDR1 antibodies specific for certain phosphorylation states.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DDR1