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Cytokeratin, HMW Antibody (KRTH/1576R) [FITC]

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Product Details

Summary
Reactivity Hu, CaSpecies Glossary
Applications IHC
Clone
KRTH/1576R
Clonality
Monoclonal
Host
Rabbit
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-54589AF350
Alexa Fluor 405
NBP2-54589AF405
Alexa Fluor 488
NBP2-54589AF488
Alexa Fluor 532
NBP2-54589AF532
Alexa Fluor 594
NBP2-54589AF594
Alexa Fluor 647
NBP2-54589AF647
Alexa Fluor 700
NBP2-54589AF700
Alexa Fluor 750
NBP2-54589AF750
Biotin
NBP2-54589B
DyLight 350
NBP2-54589UV
DyLight 405
NBP2-54589V
DyLight 488
NBP2-54589G
DyLight 550
NBP2-54589R
DyLight 594
NBP2-54589DL594
DyLight 650
NBP2-54589C
DyLight 680
NBP2-54589FR
DyLight 755
NBP2-54589IR
HRP
NBP2-54589H
Janelia Fluor 549
NBP2-54589JF549
Janelia Fluor 646
NBP2-54589JF646
Unconjugated
NBP2-53164-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-53164-100ug
Azide and BSA Free
NBP2-54589-100ug
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Cytokeratin, HMW Antibody (KRTH/1576R) [FITC] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Recombinant full-length human Cytokeratin, HMW protein (Uniprot: Q01546)
Localization
Cytoplasmic
Marker
Epithelial Marker
Specificity
This monoclonal antibody recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. monoclonal antibody AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KRT76
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Expected to show broad species reactivity.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Cytokeratin, HMW Antibody (KRTH/1576R) [FITC]

  • CK-2P
  • cytokeratin 2
  • Cytokeratin-2P
  • HUMCYT2A
  • K2P
  • K76
  • keratin 76
  • keratin, type II cytoskeletal 2 oral
  • keratin-76
  • KRT2Bcytokeratin-2P
  • KRT2Pkeratin 2p
  • KRT76
  • Type-II keratin Kb9

Background

KRT76, also known as Keratin, type II cytoskeletal 2 oral, is a 638 amino acid that is approx. 66 kDa, belongs to the intermediate filament family responsible for the structural integrity of epithelial cells, subdivided into epithelial keratins and hair keratins, and probably contributes to terminal cornification. Studies are being performed in relation to this protein and obstructive jaundice, pharyngitis, jaundice, cervical cancer, neuronitis, colorectal cancer, cervicitis, interferon and hepatitis. This protein has been shown to have interactions with ATG13, PDPK1, ULK2, GABARAP, and PRKAA1 in cytoskeleton organization pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Cytokeratin, HMW
Antibody (KRTH/1576R) ...
NBP2-54589F
Cytokeratin, HMW Antibody (KRTH/1576R) [FITC]
Species: Hu, Ca
Applications: IHC

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Bioinformatics

Gene Symbol KRT76