Flow Cytometry: Cytokeratin 7/17 Antibody (C-46) [PE] [NB500-352PE] - An intracellular stain was performed on HeLa cells with Cytokeratin 7/17 antibody (C-46) NB500-352PE (blue) and a matched isotype control (orange). ...read more
Flow Cytometry: Cytokeratin 7/17 Antibody (C-46) [PE] [NB500-352PE] - An intracellular stain was performed on HeLa cells with Cytokeratin 7/17 (C-46) antibody NB500-352PE (blue) and a matched isotype control ...read more
Cytoskeleton preparation of HeLa human cervix carcinoma cell line.
Specificity
The antibody C-46 reacts with Cytokeratin peptides 7 and 17 (54 and 46 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KRT7
Purity
Protein A purified
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Alternate Names for Cytokeratin 7/17 Antibody (C-46) [PE]
CK7
CK-7
cytokeratin 7
cytokeratin-7
K2C7
K7keratin, 55K type II cytoskeletal
keratin 7
keratin, type II cytoskeletal 7
keratin-7
MGC129731
MGC3625
sarcolectin
SCLkeratin, simple epithelial type I, K7
type II mesothelial keratin K7
Type-II keratin Kb7
Background
The protein encoded by the Cytokeratin 7 / 17 gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. (provided by RefSeq)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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