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Cytokeratin 7/17 Antibody (C-46) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, Po, Bv, Mu(-), Rb(-), Rt(-)Species Glossary
Applications WB, Flow, ICC/IF, IHC, IP, CyTOF-ready
Clone
C-46
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB500-352AF350
Alexa Fluor 405
NB500-352AF405
Alexa Fluor 488
NB500-352AF488
Alexa Fluor 532
NB500-352AF532
Alexa Fluor 594
NB500-352AF594
Alexa Fluor 647
NB500-352AF647
Alexa Fluor 700
NB500-352AF700
Alexa Fluor 750
NB500-352AF750
Allophycocyanin
NB500-352APC
Allophycocyanin/Cy7
NB500-352APCCY7
Biotin
NB500-352B
CoraFluor 1
NB500-352CL1
DyLight 350
NB500-352UV
DyLight 405
NB500-352V
DyLight 488
NB500-352G
DyLight 550
NB500-352R
DyLight 594
NB500-352DL594
DyLight 650
NB500-352C
DyLight 680
NB500-352FR
DyLight 755
NB500-352IR
FITC
NB500-352F
HRP
NB500-352H
Janelia Fluor 525
NB500-352JF525
Janelia Fluor 549
NB500-352JF549
Janelia Fluor 669
NB500-352JF669
PE
NB500-352PE
PE/Atto594
NB500-352PEATT594
PE/Cy5.5
NB500-352PECY55
PE/Cy7
NB500-352PECY7
Unconjugated
NB500-352
mFluor Violet 450 SE
NB500-352MFV450
mFluor Violet 500 SE
NB500-352MFV500
mFluor Violet 610 SE
NB500-352MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB500-352
BSA Free
NB500-352
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Cytokeratin 7/17 Antibody (C-46) [Janelia Fluor® 646] Summary

Immunogen
Cytoskeleton preparation of HeLa human cervix carcinoma cell line.
Specificity
The antibody C-46 reacts with Cytokeratin peptides 7 and 17 (54 and 46 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KRT7
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Intracellular)
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Cytokeratin 7/17 Antibody (C-46) [Janelia Fluor® 646]

  • CK7
  • CK-7
  • cytokeratin 7
  • cytokeratin-7
  • K2C7
  • K7keratin, 55K type II cytoskeletal
  • keratin 7
  • keratin, type II cytoskeletal 7
  • keratin-7
  • MGC129731
  • MGC3625
  • sarcolectin
  • SCLkeratin, simple epithelial type I, K7
  • type II mesothelial keratin K7
  • Type-II keratin Kb7

Background

The protein encoded by the Cytokeratin 7 / 17 gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB500-352JF646
Cytokeratin 7/17 Antibody (C-46) [Janelia Fluor® 646]
Species: Hu, Po, Bv, Mu(-), Rb(-), Rt(-)
Applications: WB, Flow, ICC/IF, IHC, IP, CyTOF-ready

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Bioinformatics

Gene Symbol KRT7