Complement C4c Antibody (033D-69.4.1 (10-12)) Summary
Immunogen |
Purified human C4c |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
C4B |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:100-1:2000
- Flow Cytometry 1:10-1:1000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Frozen 1:10-1:500
- Western Blot 1:100-1:2000
|
Application Notes |
Clone 1012 binds both C4c and C4 and so is not suitable for all ELISA applications. |
Control |
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
Borate buffered saline |
Preservative |
<0.1% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Protein A purified |
Alternate Names for Complement C4c Antibody (033D-69.4.1 (10-12))
Background
C4 consists of three polypeptide chains (alpha, molecular weight 95 kDa, beta, molecular weight 75 kDa and gamma, molecular weight 33 kDa) and is usually present in serum at 200-600mg/L. It is a protein of the classical complement pathway. When activated by C1s, a peptide C4a is released and the generated C4b binds C2 which is in turn cleaved by C1s to produce the classical pathway C3 convertase, namely C4b2a. C4b also has opsonin activity and binds to macrophages and neutrophils via their CR1 receptor.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Video Protocols
FAQs for Complement C4c Antibody (NB100-63261). (Showing 1 - 1 of 1 FAQ).
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Regarding the following product, could you let us know the buffer formulation?
- Disodium tetraborate decahydrate (CAS#1303-96-4) - 3.7586% Sodium Azide (CAS#26628-22-8) - <0.1%
Control Lysate(s)
Secondary Antibodies
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Isotype Controls
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