Reactivity | HuSpecies Glossary |
Applications | CyTOF-ready, Flow |
Clone | 31134 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Conjugate | Catalog # | Availability | Size | Price |
---|---|---|---|---|
Alexa Fluor 350 | IC2841U-100UG | |||
Alexa Fluor 405 | IC2841V-100UG | |||
Alexa Fluor 488 | IC2841G-100UG | |||
Alexa Fluor 594 | IC2841T-100UG | |||
Alexa Fluor 647 | IC2841R-100UG | |||
Alexa Fluor 700 | IC2841N-100UG | |||
Alexa Fluor 750 | IC2841S-100UG | |||
Specificity | Detects human Common gamma Chain/IL‑2 R gamma in direct ELISAs. |
Source | N/A |
Isotype | IgG2a |
Clonality | Monoclonal |
Host | Mouse |
Gene | IL2RG |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Publications |
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Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration. |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. Besides IL-2, the gamma chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15. It has been proposed that IL-2 R gamma be designated the common gamma chain ( gamma c). The site of molecular defects in X-linked SCID (severe combined immunodeficiency) has now been mapped to the IL-2 R gamma gene.
Secondary Antibodies |
Isotype Controls |
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