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Common gamma Chain/IL-2 R gamma Antibody (31134) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications CyTOF-ready, Flow
Clone
31134
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC2841U-100UG
Alexa Fluor 405
IC2841V-100UG
Alexa Fluor 488
IC2841G-100UG
Alexa Fluor 532
FAB2841X
Alexa Fluor 594
IC2841T-100UG
Alexa Fluor 647
IC2841R-100UG
Alexa Fluor 700
IC2841N-100UG
Alexa Fluor 750
IC2841S-100UG
Allophycocyanin
FAB2841A
Biotin
FAB2841B
DyLight 350
FAB2841D
DyLight 405
FAB2841E
DyLight 488
FAB2841K
DyLight 550
FAB2841L
DyLight 594
FAB2841M
DyLight 650
FAB2841W
DyLight 680
FAB2841Y
DyLight 755
FAB2841Z
FITC
FAB2841F
HRP
FAB2841H
Janelia Fluor 525
FAB2841JF525
Janelia Fluor 549
FAB2841I
Janelia Fluor 646
FAB2841J
Janelia Fluor 669
FAB2841JF669
PE
FAB2841P
PerCP
FAB2841C
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB2841-SP
Carrier Free
IC2841V-100UG
Carrier Free
IC2841U-100UG
Carrier Free
IC2841T-100UG
Carrier Free
IC2841S-100UG
Carrier Free
IC2841R-100UG
Carrier Free
IC2841N-100UG
Carrier Free
IC2841G-100UG
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Common gamma Chain/IL-2 R gamma Antibody (31134) [Unconjugated] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Common gamma Chain/IL‑2 R gamma
Leu23-Asn254
Accession # P31785
Specificity
Detects human Common gamma Chain/IL‑2 R gamma  in direct ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
IL2RG
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells
Publications
Read Publications using
MAB2841 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Common gamma Chain/IL-2 R gamma Antibody (31134) [Unconjugated]

  • CD132 antigen
  • CD132
  • CIDX
  • combined immunodeficiency, X-linked
  • common cytokine receptor gamma chain
  • Common gamma Chain
  • common gamma-chain
  • cytokine receptor common subunit gamma
  • gamma(c)
  • IL-2 R gamma
  • IL-2 receptor subunit gamma
  • IL2R gamma
  • IL-2R subunit gamma
  • IL2RG
  • IL-2RG
  • IMD4
  • interleukin 2 receptor, gamma
  • Interleukin-2 receptor subunit gamma
  • P64
  • SCIDX
  • SCIDX1
  • severe combined immunodeficiency

Background

The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. Besides IL-2, the gamma  chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15. It has been proposed that IL-2 R gamma be designated the common gamma chain ( gamma c). The site of molecular defects in X-linked SCID (severe combined immunodeficiency) has now been mapped to the IL-2 R gamma gene.

  1. Minami, Y. et al. (1993) Annu. Rev. Immunol. 11:245.
  2. Noguchi, M. et al. (1993) Science 262:1877.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Common gamma Chain/IL-2 R gamma Antibody (MAB2841)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


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Flow Cytometry
(2)
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(2)
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IL2RG
Uniprot