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CMYA5 Antibody

Images

 
Orthogonal Strategies: Analysis in human skeletal muscle and rectum tissues using Anti-CMYA5 antibody. Corresponding CMYA5 RNA-seq data are presented for the same tissues.
Staining of human skeletal muscle shows high expression.
Staining of human rectum shows low expression as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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CMYA5 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: FISEVSREDYGKKEISGDSEEMNINSVVTSADGENLEIQSYSLIGEKLVMEEAKTIVPPHVTDSKRVQKPAIAPPSK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CMYA5
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for CMYA5 Antibody

  • C5orf10
  • cardiomyopathy associated 5
  • cardiomyopathy-associated protein 5
  • DKFZp451G182
  • DKFZp451G223
  • DTNBP2
  • dystrobrevin-binding protein 2
  • genethonin-3
  • myospryn
  • SPRY domain-containing protein 2
  • SPRYD2
  • tripartite motif-containing protein 76

Background

CMYA5 was originally identified as the muscle-specific partner of dysbindin, (a component of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)), and as a Mef-2 target gene. CMYA5 interacts with desmin, and this association is important for the proper perinuclear localization of CMYA5 and potentially facilitates lysosome biogenesis and/or positioning. CMYA5 may also be a muscle-specific protein kinase A-anchoring protein that is dysregulated in Duchenne muscular dystrophy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CMYA5