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CMYA5 Antibody [DyLight 405]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

Order Details

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CMYA5 Antibody [DyLight 405] Summary

Immunogen
Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SPRYD2. The immunogen is located within amino acids 3810 - 3860 of SPRYD2. Amino Acid Squence: TIRWRPTTPEATETYTLE
Specificity
SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CMYA5
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CMYA5 Antibody [DyLight 405]

  • C5orf10
  • cardiomyopathy associated 5
  • cardiomyopathy-associated protein 5
  • DKFZp451G182
  • DKFZp451G223
  • DTNBP2
  • dystrobrevin-binding protein 2
  • genethonin-3
  • myospryn
  • SPRY domain-containing protein 2
  • SPRYD2
  • tripartite motif-containing protein 76

Background

CMYA5 was originally identified as the muscle-specific partner of dysbindin, (a component of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)), and as a Mef-2 target gene. CMYA5 interacts with desmin, and this association is important for the proper perinuclear localization of CMYA5 and potentially facilitates lysosome biogenesis and/or positioning. CMYA5 may also be a muscle-specific protein kinase A-anchoring protein that is dysregulated in Duchenne muscular dystrophy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol CMYA5