Recombinant Human CLPS His (C-Term) Protein Summary
Description |
A recombinant protein with a C-terminal 6xHis tag corresponding to the amino acids Met1-Gln112 of Human CLPS. Source: HEK293 (Accession #: NP_001823.1)
Store at -20C to -80C long term. After reconstitution, the product is stable at -20C for 3 months, and 2-8C for up to 1 week. |
Source |
HEK293 |
Protein/Peptide Type |
Recombinant Protein |
Gene |
CLPS |
Purity |
>90%, by SDS-PAGE |
Endotoxin Note |
< 0.1 EU/ug of the protein by LAL method |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store at -20C. |
Buffer |
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4 |
Concentration |
LYOPH |
Purity |
>90%, by SDS-PAGE |
Reconstitution Instructions |
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water |
Alternate Names for Recombinant Human CLPS His (C-Term) Protein
Background
The protein encoded by the CLPS gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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