CLPS Products

Description

The protein encoded by the CLPS gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements.

Bioinformatics

Entrez	1208 Human
Uniprot	AAH07061 Human NM_001832 Human NP_001823 Human NP_001823.1 Human
Product By Gene ID	1208
Alternate Names	colipase colipase, pancreatic pancreatic colipase preproprotein

Research Areas for CLPS

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism